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Unique gangliosides synthesized in vitro by sialyltransferases from marine bacteria and their characterization: ganglioside synthesis by bacterial sialyltransferases [Research Articles]

2013-02-15 22:39:00 (читать в оригинале)

On the basis of the results outlined in our previous report, bacterial sialyltransferases (ST) from marine sources were further characterized using glycosphingolipids (GSL), especially ganglio-series GSLs, based on the enzymatic characteristics and kinetic parameters obtained by Line weaver-Burk plots. Among them, GA1 and GA2 were found to be good substrates for these unique STs. Thus, new gangliosides synthesized by α2-3 and α2-6STs were structurally characterized by several analytical procedures. The ganglioside generated by the catalytic activity of α2-3ST was identified as GM1b. On the other hand, when enzyme reactions by α2-6STs were performed using substrates GA2 and GA1, very unique gangliosides were generated. The structures were identified as NeuAcα2-...







Pediatrician schedule:Bear 18,499
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Pediatrician schedule: Central Kent 21,857
Pediatrician schedule: Central Pencader 33,750
Pediatrician schedule: Claymont 9,695
Pediatrician schedule: Dover, DE 36,560
Pediatrician schedule: Edgemoor 6,300
Pediatrician schedule: Glasgow, DE 13,501
Pediatrician schedule: Greater Newark 70,573
Pediatrician schedule: Hockessin 13,567
Pediatrician schedule: Lower Christiana 38,118
Pediatrician schedule: Middletown, DE 12,726
Pediatrician schedule: Milford, DE 8,592
Pediatrician schedule: Newark, DE 30,371
Pediatrician schedule: North Star, DE 8,703
Pediatrician schedule: Piedmont, DE 30,902
Pediatrician schedule: Pike Creek 20,769
Pediatrician schedule: Pike Creek-Central Kirkwood 44,493
Pediatrician schedule: Seaford, DE 7,329
Pediatrician schedule: Smyrna, DE 8,917
Pediatrician schedule: Upper Christiana 25,793
Pediatrician schedule: Wilmington Manor 8,687
Pediatrician schedule: Wilmington, DE 73,069
Pediatrician schedule:Alachua 9,424
Pediatrician schedule: Altamonte Springs 39,942
Pediatrician schedule: Andover, FL 9,221
Pediatrician schedule: Apollo Beach 8,680
Pediatrician schedule: Apopka 38,809
Pediatrician schedule: Arcadia, FL 6,899
Pediatrician schedule: Atlantic Beach, FL 13,169
Pediatrician schedule: Auburndale, FL 13,987
Pediatrician schedule: Aventura 30,333
Pediatrician schedule: Avon Park 8,824
Pediatrician schedule: Azalea Park 13,076
Pediatrician schedule: Baker, FL 7,134
Pediatrician schedule: Bartow, FL 16,959
Pediatrician schedule: Bay Hill 6,113
Pediatrician schedule: Bayonet Point 31,196
Pediatrician schedule: Bayshore Gardens 20,508
Pediatrician schedule: Beacon Square 9,610
Pediatrician schedule: Bee Ridge 9,861
Pediatrician schedule: Bellair-Meadowbrook Terrace 18,423
Pediatrician schedule: Belle Glade 16,604
Pediatrician schedule: Belle Isle 6,553
Pediatrician schedule: Bellview, FL 21,761
Pediatrician schedule: Beverly Hills, FL 9,803
Pediatrician schedule: Bloomingdale, FL 23,134
Pediatrician schedule: Boca Ciega 68,887
Pediatrician schedule: Boca Del Mar 24,318


Prediction of the goat milk fatty acids by near infrared reflectance spectroscopy
Lipid–Protein Interactions in Membranes: implications for health and disease
Influence of kernel roasting on bioactive components and oxidative stability of pine nut oil
Quantitative fluorescence imaging reveals point of release for lipoproteins during LDLR-dependent uptake [Research Articles]
Lipoprotein metabolism in patients with type 1 diabetes under intensive insulin treatment
The influence of weight excess on the postprandial lipemia in adolescents
Altered membrane lipid composition and functional parameters of circulating cells in cockles (Cerastoderma edule) affected by disseminated neoplasia.
Eur. J. Lipid Sci. Technol. 1/2013
The Influence of The UV Irradiation on Degradation of Virgin Rapeseed Oils Obtained From Different Rape Varieties by Cold Press Method
Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4 [Research Articles]

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Deep eutectic solvents : Synthesis, application and focus on lipase‐catalyzed reactions

2013-02-15 22:39:00 (читать в оригинале)

AbstractIn recent years, a novel medium with similar properties to Ionic liquids but with additional advantages regarding cost, environmental impact and synthesis has been created: Deep Eutectic Solvents (DESs). These solvents result from the association between an organic salt (ammonium or phosphonium) with a hydrogen‐bond donor such as alcohols, acids or amides. To date, the availability of green, inexpensive and easy to handle solvents is almost nonexistent. Therefore, DESs currently arouse growing interest in many research fields. This review deals with the major applications of this new family of solvents with a particular focus on lipase‐catalyzed reactions such as hydrolysis, aminolysis or alcoholysis. (Source: European Journal of Lipid Science and Technology)







Pediatrician schedule:Bear 18,499
Pediatrician schedule: Brandywine, DE 82,672
Pediatrician schedule: Brookside, DE 15,569
Pediatrician schedule: Central Kent 21,857
Pediatrician schedule: Central Pencader 33,750
Pediatrician schedule: Claymont 9,695
Pediatrician schedule: Dover, DE 36,560
Pediatrician schedule: Edgemoor 6,300
Pediatrician schedule: Glasgow, DE 13,501
Pediatrician schedule: Greater Newark 70,573
Pediatrician schedule: Hockessin 13,567
Pediatrician schedule: Lower Christiana 38,118
Pediatrician schedule: Middletown, DE 12,726
Pediatrician schedule: Milford, DE 8,592
Pediatrician schedule: Newark, DE 30,371
Pediatrician schedule: North Star, DE 8,703
Pediatrician schedule: Piedmont, DE 30,902
Pediatrician schedule: Pike Creek 20,769
Pediatrician schedule: Pike Creek-Central Kirkwood 44,493
Pediatrician schedule: Seaford, DE 7,329
Pediatrician schedule: Smyrna, DE 8,917
Pediatrician schedule: Upper Christiana 25,793
Pediatrician schedule: Wilmington Manor 8,687
Pediatrician schedule: Wilmington, DE 73,069
Pediatrician schedule:Alachua 9,424
Pediatrician schedule: Altamonte Springs 39,942
Pediatrician schedule: Andover, FL 9,221
Pediatrician schedule: Apollo Beach 8,680
Pediatrician schedule: Apopka 38,809
Pediatrician schedule: Arcadia, FL 6,899
Pediatrician schedule: Atlantic Beach, FL 13,169
Pediatrician schedule: Auburndale, FL 13,987
Pediatrician schedule: Aventura 30,333
Pediatrician schedule: Avon Park 8,824
Pediatrician schedule: Azalea Park 13,076
Pediatrician schedule: Baker, FL 7,134
Pediatrician schedule: Bartow, FL 16,959
Pediatrician schedule: Bay Hill 6,113
Pediatrician schedule: Bayonet Point 31,196
Pediatrician schedule: Bayshore Gardens 20,508
Pediatrician schedule: Beacon Square 9,610
Pediatrician schedule: Bee Ridge 9,861
Pediatrician schedule: Bellair-Meadowbrook Terrace 18,423
Pediatrician schedule: Belle Glade 16,604
Pediatrician schedule: Belle Isle 6,553
Pediatrician schedule: Bellview, FL 21,761
Pediatrician schedule: Beverly Hills, FL 9,803
Pediatrician schedule: Bloomingdale, FL 23,134
Pediatrician schedule: Boca Ciega 68,887
Pediatrician schedule: Boca Del Mar 24,318


PPAR{gamma} coactivator-1{alpha} contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans [Patient-Oriented and Epidemiological Research]
Comparative study of high-dose Xuezhikang and low-dose Xuezhikang plus ezetimibe on pro- and anti-inflammatory markers
Unique gangliosides synthesized in vitro by sialyltransferases from marine bacteria and their characterization: ganglioside synthesis by bacterial sialyltransferases [Research Articles]
Altered membrane lipid composition and functional parameters of circulating cells in cockles (Cerastoderma edule) affected by disseminated neoplasia.
ERRATUM [Errata]
Influence of kernel roasting on bioactive components and oxidative stability of pine nut oil
Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo [Research Articles]
Mass spectrometry images acylcarnitines, phosphatidylcholines, and sphingomyelin in MDA-MB-231 breast tumor models [Research Articles]
Effects of soluble epoxide hydrolase inhibitor on the expression of fatty acid synthase in peripheral blood mononuclear cell in patients with acute coronary syndrome
Prediction of the goat milk fatty acids by near infrared reflectance spectroscopy

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Ovarian granulosa cells utilize scavenger receptor SR-BI to evade cellular cholesterol homeostatic control for steroid synthesis [Research Articles]

2013-02-15 22:39:00 (читать в оригинале)

This study reveals that ovarian granulosa cells retain the cholesterol homeostatic control machinery like nonsteroidogenic cells, although during active steroidogenesis, they utilize SR-BI to evade such feedback control. (Source: The Journal of Lipid Research)







Pediatrician schedule:Bear 18,499
Pediatrician schedule: Brandywine, DE 82,672
Pediatrician schedule: Brookside, DE 15,569
Pediatrician schedule: Central Kent 21,857
Pediatrician schedule: Central Pencader 33,750
Pediatrician schedule: Claymont 9,695
Pediatrician schedule: Dover, DE 36,560
Pediatrician schedule: Edgemoor 6,300
Pediatrician schedule: Glasgow, DE 13,501
Pediatrician schedule: Greater Newark 70,573
Pediatrician schedule: Hockessin 13,567
Pediatrician schedule: Lower Christiana 38,118
Pediatrician schedule: Middletown, DE 12,726
Pediatrician schedule: Milford, DE 8,592
Pediatrician schedule: Newark, DE 30,371
Pediatrician schedule: North Star, DE 8,703
Pediatrician schedule: Piedmont, DE 30,902
Pediatrician schedule: Pike Creek 20,769
Pediatrician schedule: Pike Creek-Central Kirkwood 44,493
Pediatrician schedule: Seaford, DE 7,329
Pediatrician schedule: Smyrna, DE 8,917
Pediatrician schedule: Upper Christiana 25,793
Pediatrician schedule: Wilmington Manor 8,687
Pediatrician schedule: Wilmington, DE 73,069
Pediatrician schedule:Alachua 9,424
Pediatrician schedule: Altamonte Springs 39,942
Pediatrician schedule: Andover, FL 9,221
Pediatrician schedule: Apollo Beach 8,680
Pediatrician schedule: Apopka 38,809
Pediatrician schedule: Arcadia, FL 6,899
Pediatrician schedule: Atlantic Beach, FL 13,169
Pediatrician schedule: Auburndale, FL 13,987
Pediatrician schedule: Aventura 30,333
Pediatrician schedule: Avon Park 8,824
Pediatrician schedule: Azalea Park 13,076
Pediatrician schedule: Baker, FL 7,134
Pediatrician schedule: Bartow, FL 16,959
Pediatrician schedule: Bay Hill 6,113
Pediatrician schedule: Bayonet Point 31,196
Pediatrician schedule: Bayshore Gardens 20,508
Pediatrician schedule: Beacon Square 9,610
Pediatrician schedule: Bee Ridge 9,861
Pediatrician schedule: Bellair-Meadowbrook Terrace 18,423
Pediatrician schedule: Belle Glade 16,604
Pediatrician schedule: Belle Isle 6,553
Pediatrician schedule: Bellview, FL 21,761
Pediatrician schedule: Beverly Hills, FL 9,803
Pediatrician schedule: Bloomingdale, FL 23,134
Pediatrician schedule: Boca Ciega 68,887
Pediatrician schedule: Boca Del Mar 24,318


Omega-3 long-chain fatty acids strongly induce angiopoietin-like 4 in humans [Research Articles]
ERRATUM [Errata]
Prediction of the goat milk fatty acids by near infrared reflectance spectroscopy
Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4 [Research Articles]
Eur. J. Lipid Sci. Technol. 1/2013
The Influence of The UV Irradiation on Degradation of Virgin Rapeseed Oils Obtained From Different Rape Varieties by Cold Press Method
Lipoprotein metabolism in patients with type 1 diabetes under intensive insulin treatment
Adipose tissue arachidonic acid content is associated with the expression of 5-lipoxygenase in atherosclerotic plaques
Comparative study of high-dose Xuezhikang and low-dose Xuezhikang plus ezetimibe on pro- and anti-inflammatory markers
Deep eutectic solvents : Synthesis, application and focus on lipase‐catalyzed reactions

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Assessing Smectic Liquid-Crystal Continuum Models for Elastic Bilayer Deformations.

2013-02-15 22:39:00 (читать в оригинале)

Authors: Lee KI, Pastor RW, Andersen OS, Im W Abstract For four decades, since W. Helfrich's pioneering study of smectic A liquid crystals in 1973, continuum elastic models (CEMs) have been employed as tools to understand the energetics of protein-induced lipid bilayer deformations. Among the assumptions underlying this use is that all relevant protein-lipid interactions can be included in the continuum representation of the protein-bilayer interactions through the physical parameters determined for protein-free bilayers and the choice of boundary conditions at the protein/bilayer interface. To better understand this assumption, we review the general structure of CEMs, examine how different choices of boundary conditions and physical moduli profiles alter the predicted bilayer thic...







Pediatrician schedule:Bear 18,499
Pediatrician schedule: Brandywine, DE 82,672
Pediatrician schedule: Brookside, DE 15,569
Pediatrician schedule: Central Kent 21,857
Pediatrician schedule: Central Pencader 33,750
Pediatrician schedule: Claymont 9,695
Pediatrician schedule: Dover, DE 36,560
Pediatrician schedule: Edgemoor 6,300
Pediatrician schedule: Glasgow, DE 13,501
Pediatrician schedule: Greater Newark 70,573
Pediatrician schedule: Hockessin 13,567
Pediatrician schedule: Lower Christiana 38,118
Pediatrician schedule: Middletown, DE 12,726
Pediatrician schedule: Milford, DE 8,592
Pediatrician schedule: Newark, DE 30,371
Pediatrician schedule: North Star, DE 8,703
Pediatrician schedule: Piedmont, DE 30,902
Pediatrician schedule: Pike Creek 20,769
Pediatrician schedule: Pike Creek-Central Kirkwood 44,493
Pediatrician schedule: Seaford, DE 7,329
Pediatrician schedule: Smyrna, DE 8,917
Pediatrician schedule: Upper Christiana 25,793
Pediatrician schedule: Wilmington Manor 8,687
Pediatrician schedule: Wilmington, DE 73,069
Pediatrician schedule:Alachua 9,424
Pediatrician schedule: Altamonte Springs 39,942
Pediatrician schedule: Andover, FL 9,221
Pediatrician schedule: Apollo Beach 8,680
Pediatrician schedule: Apopka 38,809
Pediatrician schedule: Arcadia, FL 6,899
Pediatrician schedule: Atlantic Beach, FL 13,169
Pediatrician schedule: Auburndale, FL 13,987
Pediatrician schedule: Aventura 30,333
Pediatrician schedule: Avon Park 8,824
Pediatrician schedule: Azalea Park 13,076
Pediatrician schedule: Baker, FL 7,134
Pediatrician schedule: Bartow, FL 16,959
Pediatrician schedule: Bay Hill 6,113
Pediatrician schedule: Bayonet Point 31,196
Pediatrician schedule: Bayshore Gardens 20,508
Pediatrician schedule: Beacon Square 9,610
Pediatrician schedule: Bee Ridge 9,861
Pediatrician schedule: Bellair-Meadowbrook Terrace 18,423
Pediatrician schedule: Belle Glade 16,604
Pediatrician schedule: Belle Isle 6,553
Pediatrician schedule: Bellview, FL 21,761
Pediatrician schedule: Beverly Hills, FL 9,803
Pediatrician schedule: Bloomingdale, FL 23,134
Pediatrician schedule: Boca Ciega 68,887
Pediatrician schedule: Boca Del Mar 24,318


Omega-3 long-chain fatty acids strongly induce angiopoietin-like 4 in humans [Research Articles]
Lipid–Protein Interactions in Membranes: implications for health and disease
The Influence of The UV Irradiation on Degradation of Virgin Rapeseed Oils Obtained From Different Rape Varieties by Cold Press Method
Eur. J. Lipid Sci. Technol. 1/2013
Deep eutectic solvents : Synthesis, application and focus on lipase‐catalyzed reactions
Phenolic acid content and sensory properties of two Spanish monovarietal virgin olive oils
Unique gangliosides synthesized in vitro by sialyltransferases from marine bacteria and their characterization: ganglioside synthesis by bacterial sialyltransferases [Research Articles]
Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr-/- mice [Research Articles]
Caspase-1 deficiency in mice reduces intestinal triglyceride absorption and hepatic triglyceride secretion [Research Articles]
Mass spectrometry images acylcarnitines, phosphatidylcholines, and sphingomyelin in MDA-MB-231 breast tumor models [Research Articles]

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Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein [Research Articles]

2013-02-15 22:39:00 (читать в оригинале)

Therapeutic agents that suppress apolipoprotein B (apoB) and microsomal triglyceride transfer protein (MTP) levels/activity are being developed in the clinic to benefit patients who are unable to reach target LDL-C levels with maximally tolerated lipid-lowering drugs. To compare and contrast the metabolic consequences of reducing these targets, murine-specific apoB or MTP antisense oligonucleotides (ASOs) were administered to chow-fed and high fat-fed C57BL/6 or to chow-fed and Western diet-fed LDLr–/– mice for periods ranging from 2 to 12 weeks, and detailed analyses of various factors affecting fatty acid metabolism were performed. Administration of these drugs significantly reduced target hepatic mRNA and protein, leading to similar reductions in hepatic VLDL/triglyceride se...







Pediatrician schedule:Bear 18,499
Pediatrician schedule: Brandywine, DE 82,672
Pediatrician schedule: Brookside, DE 15,569
Pediatrician schedule: Central Kent 21,857
Pediatrician schedule: Central Pencader 33,750
Pediatrician schedule: Claymont 9,695
Pediatrician schedule: Dover, DE 36,560
Pediatrician schedule: Edgemoor 6,300
Pediatrician schedule: Glasgow, DE 13,501
Pediatrician schedule: Greater Newark 70,573
Pediatrician schedule: Hockessin 13,567
Pediatrician schedule: Lower Christiana 38,118
Pediatrician schedule: Middletown, DE 12,726
Pediatrician schedule: Milford, DE 8,592
Pediatrician schedule: Newark, DE 30,371
Pediatrician schedule: North Star, DE 8,703
Pediatrician schedule: Piedmont, DE 30,902
Pediatrician schedule: Pike Creek 20,769
Pediatrician schedule: Pike Creek-Central Kirkwood 44,493
Pediatrician schedule: Seaford, DE 7,329
Pediatrician schedule: Smyrna, DE 8,917
Pediatrician schedule: Upper Christiana 25,793
Pediatrician schedule: Wilmington Manor 8,687
Pediatrician schedule: Wilmington, DE 73,069
Pediatrician schedule:Alachua 9,424
Pediatrician schedule: Altamonte Springs 39,942
Pediatrician schedule: Andover, FL 9,221
Pediatrician schedule: Apollo Beach 8,680
Pediatrician schedule: Apopka 38,809
Pediatrician schedule: Arcadia, FL 6,899
Pediatrician schedule: Atlantic Beach, FL 13,169
Pediatrician schedule: Auburndale, FL 13,987
Pediatrician schedule: Aventura 30,333
Pediatrician schedule: Avon Park 8,824
Pediatrician schedule: Azalea Park 13,076
Pediatrician schedule: Baker, FL 7,134
Pediatrician schedule: Bartow, FL 16,959
Pediatrician schedule: Bay Hill 6,113
Pediatrician schedule: Bayonet Point 31,196
Pediatrician schedule: Bayshore Gardens 20,508
Pediatrician schedule: Beacon Square 9,610
Pediatrician schedule: Bee Ridge 9,861
Pediatrician schedule: Bellair-Meadowbrook Terrace 18,423
Pediatrician schedule: Belle Glade 16,604
Pediatrician schedule: Belle Isle 6,553
Pediatrician schedule: Bellview, FL 21,761
Pediatrician schedule: Beverly Hills, FL 9,803
Pediatrician schedule: Bloomingdale, FL 23,134
Pediatrician schedule: Boca Ciega 68,887
Pediatrician schedule: Boca Del Mar 24,318


Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis in Ldlr-/- mice [Research Articles]
Omega-3 long-chain fatty acids strongly induce angiopoietin-like 4 in humans [Research Articles]
Comparative study of high-dose Xuezhikang and low-dose Xuezhikang plus ezetimibe on pro- and anti-inflammatory markers
Eur. J. Lipid Sci. Technol. 1/2013
Lipid–Protein Interactions in Membranes: implications for health and disease
Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo [Research Articles]
Phenolic acid content and sensory properties of two Spanish monovarietal virgin olive oils
Influence of kernel roasting on bioactive components and oxidative stability of pine nut oil
Altered membrane lipid composition and functional parameters of circulating cells in cockles (Cerastoderma edule) affected by disseminated neoplasia.
Fourier transform mid‐infrared spectroscopy evaluation of early stages of virgin olive oil autoxidation