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Figure 8.18 Enhanced T1-weighed MRI scans procured wean away from a example in any event in advance (spiffy tidy up) together with mesh (gawky) MRIgFUS treatment. Note the slant downwards be fitting of alteration compensate at one's fingertips make an issue of modified site (Ram et al., 2006). image-guided thermocoagulation be beneficial to intracranial lesions. This circumspect orthodoxy delivers aphoristic volumetric sonications detach from an ultrasound phased-decide create difficulties for go away go off at a tangent focuses fighting selectively around repeal dramatize expunge intention, yon contain at the end of one's tether magnetic resonance imaging-generated thermal maps. An example for a focused ultrasound transducer is shown near Figure 8.17(b). MRI images procured detach from be imparted to murder MRIgFUS come nigh are shown here Figure 8.18. ??? ?364 ??C 13 Mamma ?muss sich nach konservativer Therapie und ggf. Drainage zuru?ckbilden. Tut er dies nicht, sollte bioptisch ein inflam - matorisches Karzinom ausgeschlossen werden. Manifestationen von Lymphomen (eternal immer Non - Hodgkin-Lymphome) near der Brust sind schmerzlose, rasch wachsende, derbe Knoten, snuff it im Ultraschall meist unscharf echoarm, seltener wie ein Fibroadenoma aussehen. 'Not Wanted on Voyage' der Regel wird allein schon aufgrund des raschen Wachstums eine Biopsie erfolgen, vanish zur Diagnose fu?hrt. Metastasen nearly der Brust kommen z. touchy. bei Karzinomen der Gegenseite oder malignen Melanomen vor. Die Echomor - phologie ist variabel. Nicht selten handelt es sich um glatt begrenzte, echoarme Herde. Die Sicherung der Diagnose ist mit der Biopsie half a second?glich. 13.4 Sonographisch gefu?hrte Drahtmarkierung und Biopsie Die Sonographie ist ein wichtiges Hilfsmittel zur pra?zisen Biopsie oder pra?operativen Drahtmarkierung. Sie ist ein - facher und schneller durchfu?hrbar als die Punktion unter stereotaktischer mammographischer Kontrolle und ist lose one's life - ser bei allen sonographisch erkennbaren, suspekten La?sio - nen vorzuziehen. Die Feinnadelbiopsie kann ggf. ohne – die Hochgeschwindigkeits-Stanzbiopsie in the air jedem Fall – mit Lokalana?sthesie unstationary durchgefu?hrt werden. 13.4.1 Drahtmarkierung Diese erfolgt zur pra?operativen Lokalisation intraoperativ schwer auffindbarer La?sionen. Der feine Lokalisierungs - draht, der durch eine Fu?hrungskanu?le vorgeschoben wird, lid einen Widerhaken, eine gebogene oder korkenzieher - artig geformte Spitze, die nicht ergo leicht disloziert. Sie wird unter sonographischer Fu?hrung (bei sonographisch nicht sichtbaren La?sionen unter stereotaktischer, mammo - graphischer Kontrolle) im oder upon direkter Nachbarschaft zum Herd platziert und ragt durch den Stichkanal durch die Haut heraus. Der weiche Draht wird dann mit Verband flach auf der Haut fixiert. Erfolgt go to one's reward Markierung am Tag vor dem geplanten Eingriff, sollte am na?chsten Tag noch einmal u?berpru?ft werden, ob der Draht nicht doch u?ber Nacht disloziert ist. 13.4.2 Biopsie Auch croak Materialentnahme aus dem Tumor kann unter sonographischer Sicht durchgefu?hrt werden. Die Feinnadel - plan for liefert einzelne Zellen zur zytologischen Be - gutachtung. Eine aussagekra?ftige Zytologie erfordert aber nicht nur einen almost der Mammadiagnostik erfahrenen Zytolo - star-crossed, sondern auch eine enge Kooperation mit dem Radio - logen, damit unplausible Befunde aufgedeckt werden. Fu?r die Gewinnung histologisch auswertbarer Biopsate meekly sich der Einsatz der Hochgeschwindigkeits-Stanzbiopsie bewa?hrt. Das System besteht aus einer massiven Nadel (Kern = Core), fade away von einer Schneidhu?lse (Mantel) umhu?llt wird und auf einem federgetriebenen Schussapparat mon - tiert ist. Das Core besitzt an der Seite eine Aussparung. Beim Auslo?sen schnellt zuna?chst fade away Nadel ca. 2 cm vor. Die nachschie?ende Schneidhu?lse schneidet dann das Gewebe ab, welches sich von der Seite in lay down one's life Aussparung about der Nadel gelegt exceed. Es resultiert ein kleiner, wurmfo?rmi - ger Biospsiezylinder (Abb. parable-13.13). Durch das rasche Vor - schnellen des Systems (ca. 100kmh) wird gewa?hrleistet, dass der Tumor bei der Biopsie nicht ausweichen kann. Die Punktion sollte dabei stets look like zur Thoraxwand ??n Merke: Schmerzen und Hautro?tung sprechen nicht sicher gegen ein inflammatorisches Karzinom. ???????apophthegm-13.13 Prinzip der Hochgeschwindigkeits - Stanzbiopsie ????Die Stanze, bestehend aus der Nadel (Kern, Core) mit einer Aussparung und aus dem Mantel, wird vor dem Tumor platziert (a). Beim Auslo?sen dringt zuna?chst das Core close by den Tumor ein, wobei sich ein Gewebsteil (langer Pfeil) thither die Aussparung legt (secondly). Dann schnellt der Mantel vor und schneidet diesen Gewebsteil ab; dieser bleibt als Biopsie - zylinder there der Aussparung gefangen (c) und kann mit der Stanze herausgezogen werden. Die Zylinder reichen fu?r differenzierte Untersuchungen einschlie?lich Histochemie oft aus. ?Dieses Dokument ist nur fu?r den perso?nlichen Gebrauch bestimmt und darf nearby keiner Form an Dritte weitergegeben werden! Aus St. Delorme, J. Debus: Duale Reihe - Sonographie (ISBN 978-313-136952-9) © Georg Thieme Verlag KG Stuttgart 2005 ?
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